YOUR INTRAVASCULAR EYES
Forward-looking, real-time, full-color intravascular imaging at 1 millimeter. No ionizing radiation from the imaging system.
VerAvanti is developing forward-viewing imaging catheters about one millimeter in diameter. Our first product, Luce, is a single-use catheter and console designed to show the interventionalist, live and in color, what lies directly ahead of the catheter. Our scanning fiber endoscope (SFE) platform, licensed exclusively from the University of Washington, is designed to add further imaging modalities at the same small size. Both are investigational, and both are being developed to work alongside angiography, IVUS and OCT, not to replace them.
Nearly one million people are diagnosed with heart disease each year, with approximately 200,000 suffering from Chronic Total Occlusions (CTOs). This condition, which affects many catheterization patients, remains one of the most challenging issues in cardiology. Current success rates for intervention hover around just 55%, leaving the majority of patients without effective treatment. Limitations in existing imaging technology hinder doctors from accurately diagnosing and treating these life-threatening blockages, creating a critical gap in patient care.
Current imaging Technology is hindering treatment
Current imaging Technology is hindering treatment
Heart Disease and Diagnostic Demand
Over 20 million people are living with heart disease, of which 1 million have heart attacks each year. These numbers highlight a critical need for improved diagnostic solutions.
Ischemic Stroke Prevalence
About 795,000 people in the United States have a stroke each year (American Heart Association). In roughly one in four ischemic strokes, no cause is found.
Stroke Diagnostics and Causes
25% of embolic stroke patients live without knowing where the emboli originated. These patients often have recurring strokes.
Lung Cancer and the Diagnostic Gap
Lung cancer is the leading cause of cancer death in the EU, with 380,000 deaths each year. Ultra-peripheral nodules — the most critical to catch early — carry a 28–35% false-negative biopsy rate with current tools, leaving a significant portion of early-stage cases undetected.
The Terminal Bronchiole Barrier
Today's bronchoscopes cannot reach most of the smallest airways, which are under one millimeter across. The inability to navigate to this anatomy is a direct barrier to better outcomes.
Optical Coherence Tomography (OCT)
IntraVascular UltraSound (IVUS)
Limited Vision Means Higher Risk and Weaker Diagnosis
Current imaging technologies like Angiography, IVUS, and OCT are inflexible and invasive, complicating procedures and increasing infection risks.
✗ Forward-viewing imaging catheters are currently unavailable.
✗ Side viewing IVUS and OCT catheters cannot view a CTO.
✗ Angiography is unable to view a CTO due to a lack of contrast medium flow.
Experience VerAvanti's Vision: Potential Lower Risk, Enhanced Clarity and Stronger Diagnosis
VerAvanti's Scanning Fiber Endoscope (SFE) is designed to bring forward-looking, high-resolution imaging to minimally invasive vascular procedures. Unlike side-view methods, it is intended to deliver real-time, full-color visuals deep in arteries, giving clinicians a clearer view of plaques and vessel wall features.
✔ Forward-Looking Imaging: Our SFE enables clinicians to see directly ahead, overcoming traditional side-view limitations.
✔ Real-Time Clarity: High-resolution visuals reveal crucial anatomical details instantly for precise diagnosis and treatment.
✔ Immediate Intervention: Utilizing our SFE's forward-looking, real-time images, practitioners are able to perform interventions under direct endoscopic visualization.
✔ Full-Color Visualization:
Full color 1080p endoscopic video imaging from a 1mm diameter device that has access to small vessels and other small body spaces.
Disclaimer: The product shown in this video represents prototype hardware and is subject to change. Final specifications, features, and appearance may vary.
Our Potential Impact Points
We're Advancing intravascular Imaging
At the heart of VerAvanti’s Scanning Fiber Endoscope (SFE) is a piezo-actuated optical fiber that scans RGB laser light in a resonant spiral pattern. The device directs this scan from its distal tip, while reflected signals are captured through surrounding collection fibers and reconstructed into real-time, full-color video.
This laser-based angioscopy approach is designed to provide real-time and forward-looking intravascular visualization, addressing structural limitations of angiography, IVUS, and OCT. As an investigational technology, the SFE is being developed to complement existing imaging modalities and advance diagnostic precision and treatment decision-making in complex vascular disease.
Real-time visual feedback
Designed to give clinicians a live view of what lies ahead of the catheter, to support decisions during the procedure.
Single-use design
Designed for single use, so there is no reprocessing between patients.
Procedure workflow
Designed to fit existing cath lab workflow. Effects on procedure time will be measured in clinical studies.
Diagnostic information
Designed to add direct visual information to what angiography, IVUS and OCT already provide.
Our Technological Innovations
Real-Time Visual Feedback
Delivers high-resolution, live imaging to help clinicians see precise details instantly. This could reduce errors and improve decision-making for possible better patient outcomes.
Single-Use Design
Built for single-use aiming to improve sterility and eliminate cross-contamination risks. This design goal will be to improve on overall sterilization, potentially increasing patient safety and workflow efficiency.
Fiber Optic Technology
Utilizes a compact fiber-optic cable for sharp, detailed images in hard-to-reach areas. Enhanced visuals show potential to support more accurate diagnoses and targeted treatments.
Minimal Invasiveness
Fits seamlessly into procedures with minimal entry points, with the goal of reducing trauma and recovery time so patients could experience safer, faster recoveries, and hospitals increase treatment capacity.
Intelligent Image
Easy to interpret guides clinicians with enhanced visual clarity during a procedure. This would allow for better choice of therapy, streamlining complex tasks, and the possibility of overall improved patient care.
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Our Technological Innovations
Real-Time Visual Feedback
Delivers high-resolution, live imaging to help clinicians see precise details instantly. This reduces errors and improves decision-making for better patient outcomes.
Single-Use, Sterile Design
Built for single-use to ensure sterility and eliminate cross-contamination risks. This design saves time on sterilization, increasing patient safety and workflow efficiency.
Fiber Optic Technology
Utilizes a compact fiber-optic cable for sharp, detailed images in hard-to-reach areas. Enhanced visuals support accurate diagnoses and targeted treatments.
Minimal Invasiveness
Fits seamlessly into procedures with minimal entry points, reducing trauma and recovery time. Patients experience safer, faster recoveries, and hospitals increase treatment capacity.
Intelligent Image
Incorporates smart image interpretation to guide clinicians with enhanced clarity during procedures. This streamlines complex tasks, allowing for improved patient care.
Clinical Perspectives
Dr. Luis Savastano
UCSF Co-Chief of NeuroEndovascular Surgery
Medical Director, Cerebrovascular Neurosurgery
“In complex vascular procedures, key decisions often depend on understanding structures that are not directly visible with current imaging approaches. Improving visualization of what lies ahead of the catheter remains an important unmet need in both coronary and neurovascular interventions.”
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