YOUR INTRAVASCULAR EYES
A Real-Time, Forward-Looking, Full-Color Intravascular Imaging Platform — 1 mm Diameter. Radiation-Free.
At VerAvanti, we're dedicated to improving patient care with our Scanning Fiber Endoscope (SFE). Our device uses advanced imaging and is being designed to enhance accuracy, safety, and efficiency. Our goal is to assist interventionalists by addressing sightline gaps which could enable more proactive diagnosis in cardiology, neurosurgery, and peripheral artery work.
Nearly one million people are diagnosed with heart disease each year, with approximately 200,000 suffering from Chronic Total Occlusions (CTOs). This condition, which affects many catheterization patients, remains one of the most challenging issues in cardiology. Current success rates for intervention hover around just 55%, leaving the majority of patients without effective treatment. Limitations in existing imaging technology hinder doctors from accurately diagnosing and treating these life-threatening blockages, creating a critical gap in patient care.
Current imaging Technology is hindering treatment
Current imaging Technology is hindering treatment
Heart Disease and Diagnostic Demand
Over 20 million people are living with heart disease, of which 1 million have heart attacks each year. These numbers highlight a critical need for improved diagnostic solutions.
Chronic Total Occlusion (CTO) Treatment Gap
Chronic Total Occlusion (CTO) occurs in 1 of 5 patients having a cardiac catheterization. Due to limited medical imaging capabilities, only 12% of CTO patients receive treatments to clear occlusions.
Ischemic Stroke Prevalence
795,000 patients will have an embolic stroke this year, and 200,000 of these strokes have an unknown source of emboli.
Stroke Diagnostics and Causes
25% of embolic stroke patients live without knowing where the emboli originated. These patients often have recurring strokes.
Lung Cancer and the Diagnostic Gap
Lung cancer is the leading cause of cancer death in the EU, with 380,000 deaths each year. Ultra-peripheral nodules — the most critical to catch early — carry a 28–35% false-negative biopsy rate with current tools, leaving a significant portion of early-stage cases undetected.
The Terminal Bronchiole Barrier
No existing bronchoscopy device can reach the terminal bronchiole, which measures less than 1mm in outer diameter. Yet early detection at Stage IA carries a 5-year survival rate above 80%, compared to less than 10% at Stage IV. The inability to navigate to this anatomy is a direct barrier to better outcomes.
Optical Coherence Tomography (OCT)
IntraVascular UltraSound (IVUS)
Limited Vision Means Higher Risk and Weaker Diagnosis
Current imaging technologies like Angiography, IVUS, and OCT are inflexible and invasive, complicating procedures and increasing infection risks.
✗ Forward-viewing imaging catheters are currently unavailable.
✗ Side viewing IVUS and OCT catheters cannot view a CTO.
✗ Angiography is unable to view a CTO due to a lack of contrast medium flow.
Experience VerAvanti's Vision: Potential Lower Risk, Enhanced Clarity and Stronger Diagnosis
VerAvanti's Scanning Fiber Endoscope (SFE) is designed to bring forward-looking, high-resolution imaging to minimally invasive vascular procedures. Unlike side-view methods, it is intended to deliver real-time, full-color visuals deep in arteries, giving clinicians a clearer view of plaques and vessel wall features.
✔ Forward-Looking Imaging: Our SFE enables clinicians to see directly ahead, overcoming traditional side-view limitations.
✔ Real-Time Clarity: High-resolution visuals reveal crucial anatomical details instantly for precise diagnosis and treatment.
✔ Immediate Intervention: Utilizing our SFE's forward-looking, real-time images, practitioners are able to perform interventions under direct endoscopic visualization.
✔ Full-Color Visualization:
Full color 1080p endoscopic video imaging from a 1mm diameter device that has access to small vessels and other small body spaces.
Disclaimer: The product shown in this video represents prototype hardware and is subject to change. Final specifications, features, and appearance may vary.
Our Potential Impact Points
We're Advancing intravascular Imaging
At the heart of VerAvanti’s Scanning Fiber Endoscope (SFE) is a piezo-actuated optical fiber that scans RGB laser light in a resonant spiral pattern. The device directs this scan from its distal tip, while reflected signals are captured through surrounding collection fibers and reconstructed into real-time, full-color video.
This laser-based angioscopy approach is designed to provide real-time and forward-looking intravascular visualization, addressing structural limitations of angiography, IVUS, and OCT. As an investigational technology, the SFE is being developed to complement existing imaging modalities and advance diagnostic precision and treatment decision-making in complex vascular disease.
Designed for Efficient Real-Time Visual Feedback
Live imaging enables clinicians to see and react to details instantly, enhancing procedural accuracy. This real-time feedback helps reduce errors, ultimately leading to better patient outcomes and lower overall treatment costs.
Prioritizes Patient Safety with Single-Use Design
Our single-use endoscope eliminates the risk of cross-contamination, prioritizing patient safety with every procedure. This disposable approach also saves time by removing the need for complex sterilization, streamlining workflows.
Aims to Streamline Procedures and Optimize Patient Capacity
Our endoscope’s efficiency-focused design shortens procedure times, allowing hospitals to treat more patients daily. Faster interventions mean higher throughput and increased revenue potential for healthcare facilities.
Goal of Enhancing Diagnostic Accuracy
Advanced imaging technology provides clear, precise visuals, ensuring clinicians can make accurate diagnoses on the spot. This leads to more effective treatments and significantly reduces the need for repeat procedures.
Our Technological Innovations
Real-Time Visual Feedback
Delivers high-resolution, live imaging to help clinicians see precise details instantly. This could reduce errors and improve decision-making for possible better patient outcomes.
Single-Use Design
Built for single-use aiming to improve sterility and eliminate cross-contamination risks. This design goal will be to improve on overall sterilization, potentially increasing patient safety and workflow efficiency.
Fiber Optic Technology
Utilizes a compact fiber-optic cable for sharp, detailed images in hard-to-reach areas. Enhanced visuals show potential to support more accurate diagnoses and targeted treatments.
Minimal Invasiveness
Fits seamlessly into procedures with minimal entry points, with the goal of reducing trauma and recovery time so patients could experience safer, faster recoveries, and hospitals increase treatment capacity.
Intelligent Image
Easy to interpret guides clinicians with enhanced visual clarity during a procedure. This would allow for better choice of therapy, streamlining complex tasks, and the possibility of overall improved patient care.
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Our Technological Innovations
Real-Time Visual Feedback
Delivers high-resolution, live imaging to help clinicians see precise details instantly. This reduces errors and improves decision-making for better patient outcomes.
Single-Use, Sterile Design
Built for single-use to ensure sterility and eliminate cross-contamination risks. This design saves time on sterilization, increasing patient safety and workflow efficiency.
Fiber Optic Technology
Utilizes a compact fiber-optic cable for sharp, detailed images in hard-to-reach areas. Enhanced visuals support accurate diagnoses and targeted treatments.
Minimal Invasiveness
Fits seamlessly into procedures with minimal entry points, reducing trauma and recovery time. Patients experience safer, faster recoveries, and hospitals increase treatment capacity.
Intelligent Image
Incorporates smart image interpretation to guide clinicians with enhanced clarity during procedures. This streamlines complex tasks, allowing for improved patient care.
Clinical Perspectives
Dr. Luis Savastano
UCSF Co-Chief of NeuroEndovascular Surgery
Medical Director, Cerebrovascular Neurosurgery
“In complex vascular procedures, key decisions often depend on understanding structures that are not directly visible with current imaging approaches. Improving visualization of what lies ahead of the catheter remains an important unmet need in both coronary and neurovascular interventions.”
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