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Laser Ablation & Photodynamic Therapy

Aids in Guided laser and photodynamic therapies that assist in delivering deliver precision in targeted treatments, reducing procedure times. VerAvanti's SFE has a much greater depth of field allowing the scope to image from farther safer distance.


  •  Dual mode imaging and laser therapy

  • Focal spot <100 µm

  • Higher beam quality. Higher intensity.

  • Pixel-accuracy therapy.

  • Operator and fluorescent-guided photodynamic therapy

  • Full image therapy and controlled therapy location


Operator-controlled  Photodynamic Therapy. 


Ex-vivo tissue ablation by SFE



 Sequential imaging and fluorescent-guided laser therapy



SFE Fluorescence image of A549 monolayer of cell culture grown with 5-ALA. 

5-ALA induced PpIX is visualized in individual cancer cells in red color with a 405nm laser light. 







Control A549 cancer cell monolayer after laser exposure to SFE

Area of cell death created by fluorescent-guided laser exposure of SFE after incubation with 5-ALA




Cite: Woldetensae, Mikias H., Mark R. Kirshenbaum, Greg M. Kramer, Liang Zhang, and Eric J. Seibel. "Fluorescence image-guided photodynamic therapy of cancer cells using a scanning fiber endoscope." In Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XIII, vol. 8576, p. 85760L. International Society for Optics and Photonics, 2013


Full image therapy (top) and controlled therapy location (bottom)


Cite: Kirshenbaum, Mark R., and Eric J. Seibel. "Delivery of single-mode and multi-mode therapeutic laser light using a single and dual cladding optical fiber for a scanning fiber endoscope." Optical Fibers, Sensors, and Devices for Biomedical Diagnostics and Treatment XI. Vol. 7894. International Society for Optics and Photonics, 2011.

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