Fluorescence Imaging
Advanced fluorescence imaging explores cellular and molecular structures, providing deeper insights into medical conditions. This enables early detection and improved disease management strategies.
What is essential is now visible to the eye.
SFE generates simultaneous, real-time, high-definition true-color and fluorescence imaging for cancer and pre-cancerous tissue visualization.
More data. More knowledge. Informed Decisions. Improved Outcomes.
TARGETED BIOPSIES.
Increase your diagnostic yield.
RGB | Fluorescence (yellow is cancer) |
Conventional RGB videoendoscopy | Fluorescently labelled peptides for multiplexed imaging with SFE with in Barrett’s oesophagus |
Chen J, Jiang Y, Chang T, et al
Multiplexed endoscopic imaging of Barrett’s neoplasia using targeted fluorescent heptapeptides in a phase 1 proof-of-concept study
Gut 2021;70:1010-1013.
DEFINE BOUNDARIES.
Improve your outcomes.
Real-time tumor margin identification in image-guided robotic brain tumor resection
(SFE detection of brain tumor by red fluorescence)
Hu D, Jiang Y, Belykh E, Gong Y, Preul MC, Hannaford B, Seibel EJ. Toward real-time tumor margin identification in image-guided robotic brain tumor resection. Proc SPIE Int Soc Opt Eng. 2017 Feb;10135:101350D. doi: 10.1117/12.2255417. Epub 2017 Mar 3. PMID: 34321709; PMCID: PMC8315009.
Protoporphyrin IX (PpIX) detection in tumor with scanning fiber endoscope (SFE) and heath map.
Belykh, Evgenii, et al. "Scanning fiber endoscope improves detection of 5-aminolevulinic acid–induced protoporphyrin IX fluorescence at the boundary of infiltrative glioma." World neurosurgery 113 (2018): e51-e69.
HIGHLIGHT THE MALIGNANCY.
Ablate.
Brain tumor cells injected with Tumor Paint (ICG dye) in near-infrared fluorescence image captured by the scanning fiber endoscope.
Hu D, Gong Y, Seibel EJ, Sekhar LN, Hannaford B. Semi-autonomous image-guided brain tumour resection using an integrated robotic system: A bench-top study. Int J Med Robot. 2018 Feb;14(1):10.1002/rcs.1872. doi: 10.1002/rcs.1872. Epub 2017 Nov 3. PMID: 29105281; PMCID: PMC5762424.